The effectiveness of the use of xenogeneic bone blocks mixed with autologous Concentrated Growth Factors (CGF) in bone regeneration techniques

Aim

Different types of biomaterials and surgical techniques
are currently used for the augmentation of atrophic ridges in
view of implant supported restorations. The aim of this study
was to evaluate the combination of Concentrated Growth
Factors (CGF) and xenogeneic bone, mixed using a medical
device, as an effective grafting material in vertical and/or
horizontal ridge augmentation.
Materials and methods

Seven patients (3 males and 4
females), who required oral implant and ridge augmentation
surgery, were selected: 3 implants were placed during the
surgery and 4 implants were inserted 4 months later, in order
to allow complete graft integration. All implants were loaded
after a 4-month healing time. The following parameters
were assessed: a) the capability of CGF to permeate the bone
scaffold; b) the degree of bone regeneration; c) the clinical
success rate.
Results

The results obtained showed that: a) with the used
medical device porous bone scaffolds can be effectively
permeated by the CGF; b) the permeated grafting material
resulted in effective bone regeneration, as confirmed by
histomorphometric analysis; c) all implants were successfully
in function at the 12 months follow-up.
Conclusion This technique can be safely performed in the
dental office under local anesthesia, so it can be considered a
viable option in bone regeneration surgery.
The effectiveness of the use of xenogeneic bone blocks
mixed with autologous Concentrated Growth Factors (CGF)
in bone regeneration techniques to cite this article :
Gheno E, Palermo A, Buffoli B, Rodella LF. The effectiveness of the use of xenogeneic bone
blocks mixed with autologous Concentrated Growth Factors (CGF) in bone regeneration
techniques. J Osseointegr 2014;6(2):37-42.
E. Gheno1, A. Palerm o2, B. Buff oli3, L.F. Rodella3